home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
CD-ROM Today 1996 January
/
CD-ROM Today 1996 January.iso
/
dp
/
0331
/
03316.txt
< prev
next >
Wrap
Text File
|
1994-01-17
|
8KB
|
162 lines
$Unique_ID{BRK03316}
$Pretitle{}
$Title{pseudoephedrine and carbinoxamine combination}
$Subject{Carbodec Rugby Cardec-S Rondec Ross Adrenemine pseudoephedrine
carbinoxamine upper respiratory tract infections hay fever allergies sinusitis
inflammation sinuses constricting narrowing blood vessels nasal passages
swelling congestion histamine chemical allergic reaction allergy}
$Volume{}
$Log{
Rondec*0331601.scf}
Copyright (C) 1993 Publications International, Ltd.
pseudoephedrine and carbinoxamine combination
------------------------------------------------------------------------------
BRAND NAMES (Manufacturers)
Carbodec (Rugby)
Cardec-S (various manufacturers)
Rondec (Ross)
TYPE OF DRUG
Adrenemine
INGREDIENTS
pseudoephedrine and carbinoxamine
DOSAGE FORMS
Tablets (60 mg pseudoephedrine and 4 mg carbinoxamine)
Oral syrup (60 mg pseudoephedrine and 4 mg carbinoxamine per 5-ml
spoonful)
Oral drops (25 mg pseudoephedrine and 2 mg carbinoxamine per ml)
STORAGE
Pseudoephedrine and carbinoxamine combination tablets, oral syrup, and
oral drops should be stored at room temperature in tightly closed containers.
No form of this medication should ever be frozen.
USES
This drug combination is used to relieve symptoms of upper respiratory
tract infections, hay fever and other allergies, and sinusitis (inflammation
of the sinuses).
Pseudoephedrine belongs to a group of drugs known as adrenergic agents
(decongestants). They act by constricting (narrowing) blood vessels in the
nasal passages to reduce swelling and congestion.
Carbinoxamine belongs to a group of drugs known as antihistamines, which
block the actions of histamine, a chemical released by the body during an
allergic reaction. It is, therefore, used to relieve or prevent symptoms of
allergy.
TREATMENT
In order to avoid stomach upset, you can take pseudoephedrine and
carbinoxamine combination with food or with a full glass of water (unless your
doctor directs you to do otherwise).
The oral drops should be measured carefully with the dropper provided.
The oral syrup form of this medication should be measured carefully with
a specially designed 5-ml measuring spoon.
If you miss a dose of this medication, take the missed dose as soon as
possible, unless it is almost time for your next dose. In that case, do not
take the missed dose at all; just return to your regular dosing schedule. Do
not double the next dose.
SIDE EFFECTS
Minor.
Anxiety; blurred vision; constipation; diarrhea; dizziness; drowsiness;
dry mouth, nose, and throat; heartburn; insomnia; irritability; loss of
appetite; nasal congestion; nausea; restlessness; decreased sweating;
vomiting; or weakness. These side effects should disappear as your body
adjusts to the medication.
This medication can increase your sensitivity to sunlight. You should,
therefore, avoid prolonged exposure to sunlight and sunlamps. Wear protective
clothing, and use an effective sunscreen.
If you are constipated, increase the amount of fiber in your diet (fresh
fruits and vegetables, salads, bran, and whole-grain breads), exercise, and
drink more water (unless your doctor directs you to do otherwise).
Chew sugarless gum or suck on ice chips or a piece of hard candy to
reduce mouth dryness.
If you feel dizzy or light-headed, sit or lie down for a while; get up
slowly from a sitting or reclining position, and be careful on stairs.
In order to avoid difficulty in falling asleep, take the last dose of
this medication several hours before bedtime.
Major.
Tell your doctor about any side effects that are persistent or
particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about
chest pain, confusion, convulsions, difficult or painful urination, difficulty
in breathing, fainting, hallucinations, headaches, loss of coordination, mood
changes, nosebleeds, palpitations, rash, severe abdominal pain, sore throat,
or unusual bleeding or bruising.
INTERACTIONS
Pseudoephedrine and carbinoxamine combination interacts with several
other types of medications:
1. Concurrent use of it with central nervous system depressants (drugs
that slow the activity of the brain and spinal cord), such as alcohol,
barbiturates, benzodiazepine tranquilizers, muscle relaxants, narcotics, pain
medications, and phenothiazine tranquilizers, or with tricyclic
antidepressants can cause extreme drowsiness.
2. Monoamine oxidase (MAO) inhibitors (isocarboxazid, pargyline,
phenelzine, or tranylcypromine) and tricyclic antidepressants can increase the
side effects of this drug. At least 14 days should separate the use of this
drug and the use of an MAO inhibitor.
3. The action of oral anticoagulants may be decreased by the
antihistamine component of this drug.
4. Procarbazine may interact with the antihistamine component of this
drug.
5. The side effects of the antihistamine component of this medication may
be increased by quinidine, procainamide, haloperidol, and phenothiazine
tranquilizers.
6. The side effects of the decongestant component of this drug may be
increased by digoxin or over-the-counter asthma, allergy, cough, cold, diet,
or sinus preparations.
7. The blood-pressure-lowering effects of guanethidine may be decreased
by this medication.
BE SURE TO TELL YOUR DOCTOR about any medications you are currently
taking, especially any listed above.
WARNINGS
* Tell your doctor about unusual or allergic reactions you have had to
any medications, especially to carbinoxamine or other antihistamines (such as
azatadine, chlorpheniramine, clemastine, cyproheptadine, dexchlorpheniramine,
dimenhydrinate, dimethindene, diphenhydramine, diphenylpyraline, doxylamine,
hydroxyzine, promethazine, pyrilamine, trimeprazine, tripelennamine, and
triprolidine) or to pseudoephedrine or other adrenergic agents (such as
albuterol, amphetamines, ephedrine, epinephrine, isoproterenol,
metaproterenol, norepinephrine, phenylpropanolamine, and terbutaline).
* Tell your doctor if you now have or if you have ever had diabetes
mellitus, epilepsy, glaucoma, heart or blood vessel disease, hiatal hernia,
high blood pressure, myasthenia gravis, obstructed bladder or intestinal
tract, peptic ulcers, enlarged prostate gland, or thyroid disease.
* Because this drug can reduce sweating and heat release from the body,
you should avoid excessive work and exercise in hot weather, and do not take
hot baths, showers, and saunas.
* This medication can cause drowsiness. Your ability to perform tasks
that require alertness, such as driving a car or operating potentially
dangerous machinery, may be decreased. Appropriate caution should, be taken.
* Be sure to tell your doctor if you are pregnant. The effects of this
medication during pregnancy have not been thoroughly studied in humans. Also,
tell your doctor if you are breast-feeding an infant. Small amounts of this
medication pass into breast milk and may cause unusual excitement or
irritability in nursing infants.
----------------
The material contained here is "FOR INFORMATION ONLY" and should not replace
the counsel and advice of your personal physician. Promptly consulting your
doctor is the best path to a quick and successful resolution of any medical
problem.